Coupling capillary electrochromatography with electrospray Fourier transform mass spectrometry for characterizing complex oligosaccharide pools.

نویسندگان

  • Amy H Que
  • Yehia Mechref
  • Yunping Huang
  • John A Taraszka
  • David E Clemmer
  • Milos V Novotny
چکیده

To deal with the complexity of the glycan mixtures released from glycoproteins, an efficient form of micro-column separations, capillary electrochromatography, has been combined with high-performance mass spectrometry (Fourier transform ion cyclotron resonance). Contour plots have been generated from the mixtures of O-linked oligosaccharides originated from bovine mucin and bile salt-stimulated lipase, a large glycoprotein enzyme.

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عنوان ژورنال:
  • Analytical chemistry

دوره 75 7  شماره 

صفحات  -

تاریخ انتشار 2003